Ashwagandha is a powerful adaptogen used in Ayurveda to combat stress and improve energy levels. Clinical research has shown that ashwagandha can significantly reduce cortisol levels, the body's stress hormone (K. Chandrasekhar, 2012). One systematic review found that ashwagandha reduced cortisol levels by nearly 30%, helping to lower stress and anxiety (M. D. Porta et al. 2023).

Reference: “A prospective, randomized double-blind, placebo-controlled study of/.../”, 2012, K. Chandrasekhar et al. https://pmc.ncbi.nlm.nih.gov/articles/PMC3573577/
Another study by M. D Porta et al., 2023, https://www.mdpi.com/2072-6643/15/24/5015

A traditional Ayurvedic remedy made from three fruits—Amalaki, Bibhitaki, and Haritaki—Triphala is commonly used for digestive health. Modern research has shown that Triphala has significant antioxidant and anti-inflammatory properties. Triphala has been shown to support health by managing degenerative metabolic disorders, likely by inhibiting lipid peroxidation and neutralizing free radicals (Sabu and Kuttan, 2002). Triphala contains many polyphenolic compounds that give it strong antimicrobial properties, helping it fight off a wide range of harmful microorganisms (Sharma, 2015). It is included in over 1,500 Ayurvedic formulas due to its broad therapeutic uses.

Reference: Network Pharmacology, 2017, U. Chandran, N. Mehendale et. al., https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/triphala or https://www.sciencedirect.com/science/article/pii/B9780128018149000052/pdfft

Brahmi, a herb used in Ayurveda to enhance cognitive function and mental clarity, has been shown in studies to improve memory and reduce anxiety. A study from 2008 found that it improved cognitive function and reduced symptoms of anxiety in the elderly. It has also been linked to improved neuroprotection in conditions like Alzheimer’s.

Reference: “Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial”, C. Calabrese et al, 2008. https://pubmed.ncbi.nlm.nih.gov/18611150/

This herb is often used in Ayurveda for its benefits to skin health and circulation. A study from 2001 found that Gotu Kola can help enhance collagen production, which improves skin healing and reduces the appearance of scars. It’s also been shown to improve blood circulation and promote healthy brain function. Participants who suffered hypertension or ankle swelling were given 60 mg of triterpenic fraction of Gotu Kola (extract from the plant) twice daily for 8 weeks, and the health of their veins improved, in comparison with the placebo-group who did not experience these improvements. No side-effects were observed.

Reference: “Effects of the total triterpenic fraction /../", M. R. Cesarone et al., 2001. https://pubmed.ncbi.nlm.nih.gov/11666117/ “Evaluation of treatment of diabetic microangiopathy /../”, M. R. Cesarone et al., 2001. https://pubmed.ncbi.nlm.nih.gov/11666124/

Tulsi, or Holy Basil, is a revered herb in Ayurveda for its numerous healing properties, including its ability to fight stress, support immune function, and balance blood sugar. It’s been found to reduce cortisol levels, making it effective in managing stress. Lab studies has demonstrated that tulsi helps safeguard the body from injury caused by toxic chemicals by boosting the levels of antioxidant molecules like glutathione. It does this by increasing the levels of antioxidants like glutathione and by boosting the activity of enzymes like superoxide dismutase and catalase. These antioxidants and enzymes help protect cells from damage by neutralizing harmful free radicals, which can be caused by a lack of oxygen and exposure to toxic substances (M. Cohen, 2014).

Reference: “Tulsi - Ocimum sanctum: A herb for all reasons”, M. Cohen, 2014. https://www.researchgate.net/publication/271594560_Tulsi_-_Ocimum_sanctum_A_herb_for_all_reasons

Panchakarma, the Ayurvedic detoxification therapy, is a comprehensive cleansing treatment that includes oil massages, herbal baths, and fasting. One study found that ayurveda consultations, following panchakarma treatment, resulted in significant reduction of stress and anxiety after 3 months (H. Garivaltis et al, 2009).

Reference: “Ayurveda and Panchakarma: Measuring the Effects of a Holistic Health Intervention” H. Garivaltis et. al., 2009. https://pmc.ncbi.nlm.nih.gov/articles/mid/NIHMS116241/

Saffron (Crocus sativus), often used in Ayurvedic formulations for its mood-boosting properties, has been shown to have antidepressant effects. A study published in Phytotherapy Research (2014) found that saffron was as effective as standard antidepressants in treating mild to moderate depression, with fewer side effects.

Reference: “Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action”, A. L. Lopresti & P. D. Drummond, 2014, https://pubmed.ncbi.nlm.nih.gov/25384672/

One of the most well-known Ayurvedic herbs, turmeric, contains curcumin, which has been widely studied for its medicinal properties. Numerous clinical studies have demonstrated that curcumin has anti-inflammatory and antioxidant effects. It has been shown to help reduce the risk of chronic diseases like heart disease, arthritis, and even possibly playing a role in combating HIV and cancer. Turmeric has been used in Ayurveda for centuries, treating rheumatism, skin diseases, intestinal worms, diarrhea, intermittent fever, colic, allergies, asthma, psoriasis, and inflammations.

Reference: “Spicing up of the immune system by cumin”, 2007, G. C. Jagetia & B. B. Aggarwal. https://www.researchgate.net/publication/6589131_Spicing_Up_of_the_Immune_System_by_Curcumin